SubscribeRESULTS: Women who had not had a Pap smear within the recommended screening interval had higher risk of cervical cancer than women who had been screened (OR = 2.52, 95% CI = 2.19 to 2.91). This risk was similarly increased for all age groups (P(homogeneity) = .96). The risk for non-squamous cell cervical cancers (OR = 1.59, 95% CI = 1.20 to 2.11) was also increased. Women who had not had a Pap smear within the recommended screening interval had a particularly high risk of advanced cancers (OR = 4.82, 95% CI = 3.61 to 6.44). Among women who had been screened within the recommended interval, those with abnormal Pap smears had a higher risk of cervical cancer than those with normal smears (OR = 7.55, 95% CI = 5.88 to 9.69) and constituted 11.5% of all women with cervical cancer. CONCLUSIONS: Nonadherence to screening intervals was the major reason for cervical cancer morbidity. The screening program was equally effective for women of all ages and was also effective against non-squamous cancers.[emphasis added] Etc, etc.
In the US, the situation is considerably better, with deaths from cervical cancer declining rapidly since the introduction and widespread use of the Pap test for screening in the 1930’s and 1940’s, to an estimated 4,400 deaths in the year 2001.2 Currently, the age-adjusted death rate from cervical cancer per 100,000 population in the US is reported as 2.4. In contrast, rates in countries such as Mexico (14.0), Venezuela (10.8), and Romania (10.5) are markedly higher.3The paper provides citations. It seems that you need to perform a lot of PAPs to catch the cancers that you can treat, but cervical cancer isn't something you want to get and not catch.
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posted by parmanparman at 5:51 PM on July 8