SubscribeProlonged upright posture results in some degree of pooling of blood in the lower extremities that can lead to diminished intracardiac volume. This phenomenon is accentuated if the individual is dehydrated. The resultant arterial hypotension is sensed in the carotid body baroreceptors, and afferent fibers from these receptors trigger autonomic signals that increase cardiac rate and contractility. However, pressure receptors in the wall and trabeculae of the underfilled left ventricle may then sense stimuli, indicating high-pressure C-fiber afferent nerves from these receptors. They may respond by sending signals that trigger paradoxical bradycardia and decreased contractility, resulting in additional and relatively sudden arterial hypotension.Here's my translation of that (though I'm not an M.D.): if you're standing or sitting in one place for too long, particularly if you're dehydrated, blood can pool in your legs and lower abdomen. This is bad because then it's not available to do its job, namely carry oxygen around. Your body notices the lack of blood via pressure receptors (think of the oil pressure gauge in a car), and initially tries to compensate by making your heart beat faster. But when that doesn't cause the problem to resolve itself, your body slows the heart down very suddenly, actually dropping your blood pressure even further -- sending a message to the brain in a very direct way. The result is that your brain does a sort of panic-stop: it sends out a signal to relax everything, everywhere. The result is a loss of consciousness (due to low BP) and you hit the floor.
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posted by parkerama at 11:38 PM on September 26, 2007