Sedation effect from amitriptyline, does it fade?
December 14, 2013 11:17 AM Subscribe
My neurologist has prescribed amitriptyline (Elavil) for migraine +/- sleep issues. I took the first dose, 10 mg, last night. Today I am Elmer Fudd. I have felt substantially sedated all day, and this is not ok if it stays! I'm trying to decide whether I should continue with another dose tonight, or discontinue & call the doc on Monday. Dr. Google tells me that the half-life of the drug is 10-50 h., so I'm leaning towards no. So, if you have experience with amitriptyline - is the sedative effect an initial one that fades, or will it stay (or get worse)?