Bathsheba Grossman is an American sculptor, notable in part for mathematically and biologically inspired sculptures printed in metal. Another line of artwork consists of mathematical and biological data etched in glass. I have seen the results of the process up close and they are striking. I would like to find data to make a laser etching of a human α1β2γ2 GABA A receptor. I have done a bit of Googling around, but most of the PDB files I have been able to find are just for associated proteins. Does anyone have an idea of where I might be able to find the right sort of data for the whole receptor?
My +1 is outfitting the molecular biology and biochemistry side of a physics lab. He would like to get books (electronic and/or paper) to fulfill two needs: 1. protocols and reference - for in lab use 2. history or textbook of molecular biology - to help familiarize physics people with the field. Looking for suggestions for solid books that are readable and have good figures. [more inside]
I am applying for tenure-track molecular biology faculty positions in the US. My skills are also in high demand in industry. Offers for faculty jobs I apply to now should come anywhere from late Feb to early May with a lot of flexibility on how long I have for acceptance. I suppose that biotech industry positions will have a much shorter timescale from application to their decision and how long I have for mine, but I'm not entirely sure. If I want to maximize my options in the spring, when should I start inquiring about industry jobs? [more inside]
I'm looking for good free software tools for doing basic molecular biology work - sequence alignments, DNA-protein translation, restriction mapping, and PCR primer design. Got any recommendations? [more inside]
I'm looking for a sampling of where biochemistry students wind up after college. Basically, where did you start out and where did you end up? How difficult was it for you to find a position out of college? [more inside]
Has there been any critical recognition of the similarity of the sculptures of Jachin and Boaz from Matthew Barney's Cremaster 3 to important helical structures (the DNA helix and the alpha helix) from molecular biology? [more inside]
What's new and exciting in the fields of molecular biology, biochemistry, genetics? I'm looking for an exciting/interesting journal article to present to my classmates along the lines of heterologous eukaryotic expression of a gene or gene therapy utilizing knockouts as a technique or with an emphasis on transgenic organisms. I could, of course, slog through the journals on my own and guess at what might be exciting in the field, but I thought I would ask the hive first. Any biochemists or molecular biologists out there want to give this a go? Citations would be incredibly helpful.
Plasmids, prokaryotes, and markers... [more inside]
MolecularBiologyFilter: How can knocking out one copy of a gene have the same effect as a mutation that leads to increased activity? [more inside]
Attention molecular biology nerds: have you any experience with photoinitiation of acrylamide gel polymerization? [more inside]
MolecularBio geeks: What's the best sequence analysis software for OS X? [more inside]
Does anyone have a good, detailed protocol for nuclear DNA extraction from a human (or other mammalian) sperm sample? [more inside]