99 posts tagged with genetics.
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Unlikely cousins on 23andme

My knowledge of biology is minimal, so bear with me. I'm on 23andme, which shows me a list of relatives. From the names and biographical information, most look accurate (same South Indian ethnicity as mine). However, there are 2 people on the list who are white American and don't appear to have any Indian connection, who share about 0.10% of my DNA. I don't have white ancestors either, AFAIK. Is this a sequencing error? A coincidental common mutation? Or an actual shared ancestry?
posted by redlines on Oct 30, 2016 - 16 answers

I was told there would be no math.

I've crossed a bunch of plants with one another, and now have a bunch of berries on those plants. Each berry can contain way more seeds than I have room to pot up and grow out individually, so I'm trying to find the point of diminishing returns, where potting up additional seedlings stops giving me new and interesting results, but my math background is inadequate. [more inside]
posted by Spathe Cadet on Aug 21, 2016 - 13 answers

Best books of current human migration science

What are the most current books that explore the fields of research relating to the anthropology and genetic work of determining who migrated where and when in human history? [more inside]
posted by xarnop on May 22, 2016 - 1 answer

Will I develop muscular dystrophy?

I recently had a 23 and Me genetic panel done. Questions about the results of things I have come back positive as... [more inside]
posted by anonymous on Dec 19, 2015 - 8 answers

Are You My Daddy?

Asking for a friend: "There is some question about who my father is - the man who raised me (Daddy) or his brother (Uncle) The only family DNA I have is from my nephew who is my sister's son, definitely Daddy's grandson. My nephew and I share 1610 cM. Is this enough information to determine who my father is?"
posted by Allee Katze on Sep 24, 2015 - 5 answers

Genetic testing for nerds

I'm thinking of getting my genome sequenced by 23andme. However, I am not interested in a responsive, user-friendly experience. I want to get my raw data, upload it to Promethease, and also play around with it myself. I also have some privacy concerns, and am wary of the family/ancestry features. Help me think this through. [more inside]
posted by vogon_poet on Aug 29, 2015 - 12 answers

Genetic testing for Pick's Disease

Two part question. First - my family strongly suspects my father has late-stage Pick's Disease, which is a form of fronto-temporal dementia. It can't be truly diagnosed until an autopsy though. He's post-65. He has most of the symptoms. So I have two very related questions. [more inside]
posted by anonymous on Jun 27, 2015 - 5 answers

alzheimers and moms: what's the latest?

I've just been reading a review of the latest film treatment of Alzheimers ("Still Alice"), which has the character inherit her early-onset version of the disease from her alcoholic father. But at least for a while, it seemed like the medical thinking linked Alzheimer's to mitochondrial DNA, so that it would be linked to the mother's genetic profile. I realize that it's a hideously complex disease, with or without alcoholism as a factor, but is the maternal-line theory valid?
posted by mmiddle on Jan 16, 2015 - 5 answers

Online resources for studying genetics?

I'm gearing up for a final exam in my undergraduate level genetics class, and I'm finding my textbook (iGenetics by Peter Russell) and the professor's slides are not sufficient for my study needs. I'd really like some more sources to review over the next few days. The topics on this final exam are operons, conjugation/transformation/transduction, genomic imprinting, and differential gene expression. Do you have any favorite online resources for studying these subjects? The more specific the better (i.e. a specific youtube playlist or a specific section of a website, rather than just a generally genetics related channel or site).
posted by ocherdraco on Dec 18, 2014 - 3 answers

Anatomical structures, medical conditions, etc. named after women?

Can you help me find pieces of medical terminology named after women, or female medical eponyms? I'm talking about anatomical structures, diseases, conditions, collections of symptoms - hell, even proteins or genes would work! Wikipedia has a list of human anatomical parts named after people, but none of the people listed appear to be female. [more inside]
posted by lizzicide on Dec 14, 2014 - 6 answers

Generational impact of incest and intermarriage between cousins

My mother is convinced she is the product of an incentious relationship by her mother and her grandfather. Genetic testing proved inconclusice due to the poor quality of the samples available from her grandfather (my greatgrandfather) and her mother (my grandmother) as both were deceased by the time the testing was done. My parents are first cousins (my maternal and my paternal grandmothers are sisters). I have a child by my SO (not a relative). I constantly worry for his long-term health. This whole issue was extremly worrying to me during pregnancy, but I expected my worries to decrease once he is older, and especially as he continues to develop fine physically and mentally, developing right on target. He will soon turn 6 and I worry more than ever, every little quirk gives me sleepless nights. [more inside]
posted by anonymous on Oct 23, 2014 - 25 answers

Where is my Native American?

For years, I've assumed I was 1/32nd Native American. I've seen a picture of my great-great-grandmother, who's clearly part Native American. The story was always that she was half. That would make my great-grandfather a quarter, my grandmother 1/8th, my mom 1/16th and me 1/32nd. Except that when I look at 23andme results, there's no indication of that in my ancestry composition. Native American comes in at 0.0%. Is there a chance my results could be off?
posted by tallthinone on Sep 24, 2014 - 36 answers

That's Allopatric speciation, Folks!

How quickly does genetic drift lead to speciation in higher life forms? More specifically, how long would it take for two isolated human populations, exposed to similar but not identical selective pressures, to become incapable of producing viable offspring due to genetic drift? [more inside]
posted by itstheclamsname on May 18, 2014 - 10 answers

Does having an organ transplant affect home genetic testing?

My relative wants to take a 23andMe DNA test, but he has a heart and a kidney transplant (from 5 years ago). I have read about the possibility of chimerism (which I understand to be the presence of two sets of cells) in transplant recipients, and I am wondering if such a condition would affect the saliva-based DNA testing of 23andMe? And also, how common is this condition in transplant patients? Is there only really a pretty small chance that this will affect his test?
posted by foxinthesnow on May 3, 2014 - 4 answers

99% chance of Alzheimer's Disease

Chatting casually with a bioinformatician yesterday, I was told that I have 99% chance of developing Alzheimer’s disease, based only on my mother and father’s nationalities. How should I take this claim? [more inside]
posted by mister_kaupungister on Apr 21, 2014 - 27 answers

But we are all X-Men!

You Are Not My Genetic Counselor, But Neither Are Any of these Self-Styled Uncertified Genetic Counselors on the Internet. The latest fad/quackwatch for desperate parents and patients dealing with autism spectrum disorders or chronic illness seems to be running raw data from consumer genetics testing through an app (or paying hundreds of dollars more for a "nutrigenomics" panel) to check for polymorphisms. Consumers get back lists (helpfully color-coded like traffic lights) of normal, heterozygous, and homozygous gene pairs, but how common are these variations to begin with (setting aside how often they are actually expressed as illness)? [more inside]
posted by blue suede stockings on Mar 19, 2014 - 3 answers

A codon pun?

I saw a license plate that said CCA TGG, and I was wondering if this is a clever pun by a geneticist. [more inside]
posted by Mayhembob on Mar 9, 2014 - 8 answers

King Henry VIII's dream come true...

Biologists and Staticians... what's going on here? There hasn't been a female born in my husband's family in two generations. Help solve the brothers' debate about what's causing this, and what the odds of our pregnancy being male or female is. [more inside]
posted by jrobin276 on Feb 11, 2014 - 16 answers

Archetypal Images and Genetics

Does anyone know about any research that shows that the meaning of symbols is passed down genetically? [more inside]
posted by orsonet on Jan 19, 2014 - 4 answers

Help me get up-to-date in genetics and immunology.

Please recommend some up-to-date textbooks in genetics and immunology. [more inside]
posted by Protocols of the Elders of Sockpuppetry on Dec 14, 2013 - 2 answers

23andMe for Jewish Genetic Testing

Is 23andMe sufficient for the genetic testing my fiance and I require before getting married (Jewish genetic testing)? [more inside]
posted by RUPure on Nov 12, 2013 - 16 answers

Sensitive Skin -- What are the possible causes?

Hi, I am hoping to get to the bottom of something that has been driving my nuts ever since I was a kid. I have hypersensitive skin to touch. It turns red (or sorta faded yellow/white) the second it is pressed. If I poke my arm with a finger I can see a circle that fades from red, yellowish to white and then it goes back to normal. All within 10-15 seconds. I noticed it being annoying whenever I went for a haircut and scissors glided along my forehead. It would leave a red mark for the next 5-10 minutes. Secondly whenever I went in for a massage, the therapist would joke that I bruise easily and turn red within a second of being touched. Could my blood type be the reasoning behind this? I am ' A- ' and I am just taking a wild shot at dark here. Was hoping someone with experience could clue me in to why my skin acts the way it does. My roots are predominantly southern-european with some distant Turkish/Ottoman ancestry. Green eyes and moderately white skin complexion. I'm not Irish-white by any means but white like most southern Europeans. Thank You for your insight!
posted by bostonhill on Nov 7, 2013 - 8 answers

How to respond to someone else's quest to find their sperm donor?

Asking for a friend. In a nutshell: My friend has been contacted by at least two different people seeking to identify their biological father, a sperm donor. My friend has enough information to make an educated guess about the identity of the sperm donor. How should he proceed? [more inside]
posted by Orinda on Sep 16, 2013 - 9 answers

How does gene selection work in honeybees?

This question has several parts, so please bear with me while I suss it all out. I have a specific question about inbreeding, and an open ended one about selecting traits in animals in general and honeybees in specific, though anyone familiar with genetics and animal husbandry can help me here. [more inside]
posted by TheTingTangTong on Sep 5, 2013 - 2 answers

A site or app that will let me check for DNA relatives

I'm trying to determine whether my dad is really my dad. I have my DNA raw data and my dad's raw data from 23andme, but results are not yet calculated for relatives. [more inside]
posted by anonymous on Jul 26, 2013 - 7 answers

I love you so much, and I want to never have your baby.

My boyfriend and I haven't been together for a very long time, but it has already started to feel very serious and I see the potential for a longterm future together. We are both extremely close with our families and I know that family life and children are a huge priority for both of us. We're on the same page there. However... By extraordinary coincidence we both suffer from the same rare, semi-inheritable disease. [more inside]
posted by anonymous on May 10, 2013 - 25 answers

What's this movie: genetic engineering gone wrong, set in an office

I saw a trailer a while (1,2 years?) ago. The plot had something to do with either a company or research project that had gone wrong. Genetically messed-up creatures and people were roaming around inside an office block. In the trailer, a guy is at the photocopier, and a large, human-faced spider thingy creeps up behind him. [more inside]
posted by flutable on Apr 5, 2013 - 9 answers

Find the structure of nucleic acid from proportions of nucleotides

How can you tell the physical and chemical structure of a nucleic acid based on a sample's proportions of nucleotides? [more inside]
posted by johnofjack on Feb 9, 2013 - 20 answers

I want to be the next Professor X.

I know I want to study genetics but I don't know where to go from there. What kind of things in genetics did Professor X and the Drs. Suresh on Heroes study? I want to study that. [more inside]
posted by acthelight on Dec 14, 2012 - 10 answers

Genetics and schizophrenia, pregnancy risks

Genetics and schizophrenia, what are the risks in having children? [more inside]
posted by cloudscratcher on Dec 9, 2012 - 12 answers

Genetics Research and Networking

Career mashup: Genetics Research and Networking. [more inside]
posted by Tell Me No Lies on Nov 26, 2012 - 5 answers

Understanding current gene therapy research

How can I learn enough about biology and genetics to understand current research into cystic fibrosis? [more inside]
posted by Stark on Aug 2, 2012 - 14 answers

Sloppy MicroChips: Can a fair comparison be made between biological and silicon entropy?

Was reading about microchips that are designed to allow a few mistakes (known as 'Sloppy Chips'), and pondering equivalent kinds of 'coding' errors and entropy in biological systems. Can a fair comparison be made between the two? [more inside]
posted by 0bvious on Jun 5, 2012 - 4 answers

Have any of you participated in or led the genetics lab using fruit flies?

Have any of you participated in or led the genetics lab using fruit flies? [more inside]
posted by shrimpsmalls on May 19, 2012 - 12 answers

Why don't African violets propagate "true"?

Why do African violets not propagate "true," in regards to color patterns? [more inside]
posted by fiercecupcake on Apr 19, 2012 - 1 answer

What are my options for secretly determining paternity?

What are my options for secretly determining paternity? It's come to my attention, thanks to some casual conversation about blood types, that my blood type is possibly incompatible with my parents'. This is not something I want either parent to know I know, until I'm damn sure. [more inside]
posted by anonymous on Mar 10, 2012 - 12 answers

To spot-tone or not to spot-tone

Can you ever really change your body shape with specific exercises? [more inside]
posted by everydayanewday on Feb 23, 2012 - 24 answers

Help me learn the ABCs of A,C,T and G!

Looking for an awesome primer on genetics! It should start somewhere around the highschool level, and continue through to some college-level material. Bonus points if it touches on some recent developments and research. Oh! And readability is key. [more inside]
posted by Afroblanco on Jan 13, 2012 - 5 answers

Breeding Personality

If personality isn't supposed to be genetic, then how are pet breeds able to be differentiated by personality? [more inside]
posted by divabat on Jan 5, 2012 - 15 answers

Which X Chromosome did I inherit from my mother?

Which X Chromosome did I inherit from my mother? [more inside]
posted by brownrd on Aug 27, 2011 - 12 answers

How do you set up a new molecular genetics lab?

A question for all the molecular geneticists out there: how did you go about setting up your first lab? [more inside]
posted by Alice Russel-Wallace on Aug 27, 2011 - 6 answers

Questions about biology from the movie Rise of the Planet of the Apes

Questions about biology, genes, humans and apes, courtesy of the movie Rise of the Planet of the Apes. SPOILERS WITHIN. [more inside]
posted by Brandon Blatcher on Aug 19, 2011 - 8 answers

How do I avoid turning into my mom?

After seeing my mother suffer from myriad health problems due to her depression and obesity, I am freaking out that my destiny is written in my genes. Please help figure out how to change the things I can and accept the things I cannot. I also welcome stories/advice from children of unhealthy people who learned from their parents' mistakes. [more inside]
posted by anonymous on Jun 30, 2011 - 17 answers

Do my kittens have two dads?

Do my kittens have two dads? They come from the same litter but have different hair length. [more inside]
posted by vegetable100% on Jun 21, 2011 - 22 answers

Fun with fake science, Star Trek Mirror Universe edition

I don't know enough about genetics generally, and RNA specifically, to work through this Star Trek RPG story hook. Please hope me. [more inside]
posted by AugieAugustus on May 6, 2011 - 12 answers

I am large, I contain multitudes

How common is human chimerism of the sort described in this Boing Boing post? What implications does the existence of chimerism have for DNA testing, especially with respect to the criminal justice system? Does it pose a practical limit on the usefulness of DNA evidence, or just a theoretical one? Has chimerism come up in any cases, or been considered as a problem in legal scholarship?
posted by gerryblog on Mar 23, 2011 - 15 answers

(Homework filter) Snappy genetics poster title needed

My poster group needs a short, snappy title (preferably with a terrible newspaper style pun). And we've got nothing. [more inside]
posted by stillnocturnal on Feb 26, 2011 - 15 answers

I'm sure I have relatives...somewhere.

[biogeography filter] Both of my parents are adopted. How can I find out more about my ethnic heritage? Complicating factors inside. [more inside]
posted by easy, lucky, free on Feb 17, 2011 - 11 answers

NPR special on a certain eccentric pioneering biologist...

Trying to find an NPR program about an eccentric pioneer of genetics who insisted on black laboratories? [more inside]
posted by brownbat on Feb 12, 2011 - 5 answers

Bald Patches in Beard - Harbinger of Cancer?

YANMD but: can a bald patch in the beard be an indicator of oral cancer? More detail below. [more inside]
posted by rahnefan on Jan 30, 2011 - 9 answers

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