From a medical/science standpoint, what are the limiting factors that make it difficult to produce pharmaceutical drugs that do not have negative side effects?
posted by 6spd
on Feb 17, 2013 -
I would like to know what options are available to me to enhance (or indeed the opposite) video streams - What I'd specifically like to do is download specific youtube footage (personal use) and render it with a jumpy black and white Pathe film-like quality. What would be the best approach to achieve this? - And please take into account that I have no Apple products to hand and very limited experience in manipulating the moving picture.
posted by mattoxic
on Nov 27, 2012 -
Digital artists: What is this cool, grainy Photoshop texture used in webcomics and how do I make it too? [more inside]
posted by iadacanavon
on Nov 6, 2012 -
Is there a real world referent for that bleeping typing noise used in some films as a text (usually a location note) appears on the screen? It's a similar thing to that chunka-chunka typing sound used in the X-Files when the location of a new scene would be announced, but it's like a very rapid, high-pitched "beedeebeedeebeedeebeep" sound played while the letters appear. [more inside]
posted by col_pogo
on Jan 18, 2012 -
After 3 weeks on 75 mg of zoloft (previously was on 50 mg) the side effects are helping with my intense anxiety. In fact, I'm pretty apathetic. I'm also having difficulty sleeping and then difficulty waking up, to the point that I slept well into the afternoon today (very unusual for me). I find myself clenching my jaw and rather jittery. And I feel strangely separated from reality, as if I'm in a fog. As hard as it is to fall asleep I feel like I'm fighting sleep all day. Has anyone experienced these symptoms but stayed on the medication and found that they were able to stabilize?
posted by bunderful
on Aug 13, 2011 -
A little while back I heard a bass guitar player with some kind of amazing live looping set-up - what on earth was it? I keep wondering what he was doing. All I could see was that he was grabbing (sampling) things he was playing, as he was playing them (ie while he was continuing to play), using foot pedals of some sort, and then incorporating those loops into the rest of the track. Amazing. But how?
posted by monster max
on Oct 18, 2009 -
Prompted by the success of a previous post
, I have another special effects question. Is there a term of art for the stuff like extra model kit parts and other doodads glued to a model to give it a sense of scale and complexity? [more inside]
posted by bartleby
on Oct 8, 2009 -
GuitarGearFilter: I'm a semi-skilled guitarist looking to add pedals and effects to my rig. I like the idea of those several-pedals-in-one processor thingies, but I'm baffled by the array of stuff out there and a bit wary of the opinions of the possibly-commissioned staff of the local music store. [more inside]
posted by Schlimmbesserung
on Aug 4, 2006 -