Cool Tools is along those lines, though it's concerned with functionality rather than aesthetics. I also like Book of Joe. posted by holgate at 7:48 AM on January 20, 2006
Occasionally Coolhunting, although they're more into aesthetics than usability.
I may post more when I get home, I don't have my full RSS feed list at work. posted by mikeh at 8:03 AM on January 20, 2006
Design sponge, which, like Coolhunting, is a bit more aesthetics-focussed. posted by Plutor at 8:41 AM on January 20, 2006
Also check out Infosthetics. Maybe not quite as practical as the other sites mentioned here, but very cool! posted by sanitycheck at 2:12 PM on January 20, 2006
posted by holgate at 7:48 AM on January 20, 2006