Physiologically, a determined adversary can be stopped reliably and immediately only by a shot that disrupts the brain or upper spinal cord. Failing a hit to the central nervous system, massive bleeding from holes in the heart or major blood vessels of the torso causing circulatory collapse is the only other way to force incapacitation upon an adversary, and this takes time.The parts following that on page 11 about other physiological and psychological factors in wounding and incapacitation are pretty interesting as well.
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posted by Ironmouth at 3:13 PM on June 9, 2012 [1 favorite]