Nerve cells do not split and divide like other cells in your body. Rather, nerve cells must either fix themselves or have a strategy to develop new nerve growth, and both processes require BDNF. Thus, one way to stimulate BDNF is to injure nerve cells.
It is this latter strategy that SSRI antidepressants utilize – in a manner never intended by Mother Nature. The details of this rather bizarre method of operation are explained in a review article ...
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