How do I graph pharmacokinetics?
September 30, 2009 9:42 AM Subscribe
How can I visualize the pharmacokinetics of a drug? Is there a way to create a graph of the blood plasma levels of a drug including the fluctuations caused by time of administration?
posted by ladypants to health & fitness (10 answers total) 1 user marked this as a favorite
To make a long story short, my doctor changed one of my prescriptions and I'm curious how it will affect the plasma level of the drug.
I can find the half life and some other pharmacokinetic info on the drug through the FDA web site and the prescribing information, but I'm having trouble understanding the steady state level of the drug and fluctuations in blood plasma levels due to different time release formulations and times of dosage. I haven't been able to find any blood plasma curves drawn out. Basically, I wanna SEE what's going on.
How can I create a graph of this information using Excel or some other software? Is there some magic software or website designed to do precisely this? Ideally I'd like to be able to input different doses and times of administration to see how they affect blood plasma levels over time. I have access to MatLab if that helps (but no idea how to use it), Excel, SPSS. I haven't done calculus in about a decade but consider myself competent at basic algebra and number crunching. I'd be up for some calc review if it ill help me wrap my head around all this.